Author

J. Tyler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Bennett· 1 shared A. Nussenzweig· 1 shared A. Tubbs· 1 shared B. P. Sleckman· 1 shared B.-R. Chen· 1 shared C.-C. Chen· 1 shared D. Zong· 1 shared E. Rainero· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Bennett

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration

M. Llanses Martinez, K. Nan, Z. Bao, R. Bacchetti, S. Yuan, J. Tyler, X. Le Guezennec, F. A. Bard, E. Rainero

This study identifies 2β1 integrin and MAP3K1/p38 signaling as regulators of ECM internalization, which promotes cancer cell migration and invasion in breast and pancreatic cancers.

bioRxiv · Jan 11, 2024 · PreprintCancer Biology

LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells

B.-R. Chen, Y. Wang, A. Tubbs, D. Zong, F. Fowler, N. Zolnerowich, W. Wu, A. Bennett, C.-C. Chen, W. Feng, A. Nussenzweig, J. Tyler, B. P. Sleckman

The paper shows LIN37 prevents DNA end resection and HR in quiescent cells independently of 53BP1, unlike in cycling cells.

bioRxiv · Apr 21, 2021Cell Biology