Author

D. Zong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Nussenzweig· 3 shared A. Bennett· 1 shared A. Tighe· 1 shared A. Tubbs· 1 shared A. V. Pankajam· 1 shared B. P. Sleckman· 1 shared B.-R. Chen· 1 shared C.-C. Chen· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. Nussenzweig

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR

D. Zong, N. C. Koussa, J. A. Cornwell, A. V. Pankajam, M. Kruhlak, N. Wong, R. Chari, S. D. Cappell, A. Nussenzweig

This study maps the cellular response to WRN loss in MSI-H cancers, showing DNA damage accumulation and cell death, and suggests dual targeting of WRN and ATR as a therapeutic strategy.

bioRxiv · Jul 28, 2023Cancer Biology

LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells

B.-R. Chen, Y. Wang, A. Tubbs, D. Zong, F. Fowler, N. Zolnerowich, W. Wu, A. Bennett, C.-C. Chen, W. Feng, A. Nussenzweig, J. Tyler, B. P. Sleckman

The paper shows LIN37 prevents DNA end resection and HR in quiescent cells independently of 53BP1, unlike in cycling cells.

bioRxiv · Apr 21, 2021Cell Biology

TP53 loss initiates chromosomal instability in high-grade serous ovarian cancer

D. Bronder, D. Wangsa, D. Zong, T. J. Meyer, R. Wardenaar, P. Minshall, A. Tighe, D. Hirsch, K. Heselmeyer-Haddad, L. Nelson, D. Spierings, J. C. McGrail, M. Cam, A. Nussenzweig, F. Foijer, , S. S. Taylor

This study shows that TP53 loss in fallopian tube epithelial cells drives chromosomal instability through cell cycle deregulation, without requiring additional mutations.

bioRxiv · Mar 12, 2021Cancer Biology