Author

J. V. Swain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

D. J. Phuong· 2 shared J. C. Reed· 2 shared J. R. Lingappa· 2 shared V. R. Lingappa· 2 shared A. Kitaygorodskyy· 1 shared B. C. Barajas· 1 shared B. Freeman· 1 shared C. R. Hurt· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

D. J. Phuong

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Author profile →

2 papers

Recent·Most cited

Identification of an antiretroviral small molecule that appears to be a host-targeting inhibitor of HIV-1 assembly

J. C. Reed, D. Solas, A. Kitaygorodskyy, B. Freeman, D. T. B. Ressler, D. J. Phuong, J. V. Swain, K. Matlack, C. R. Hurt, V. R. Lingappa, J. R. Lingappa

This paper identifies two small molecules that inhibit HIV-1 assembly by targeting host factors involved in Gag assembly, showing efficacy against drug-resistant strains and lacking resistance mutations in Gag.

Journal of Virology · Jan 13, 2021Peer-reviewedMicrobiology

The ABCE1 capsid assembly pathway is conserved between primate lentiviruses and the non-primate lentivirus feline immunodeficiency virus

J. C. Reed, N. Westergreen, B. C. Barajas, D. Ressler, D. J. Phuong, J. V. Swain, V. R. Lingappa, J. R. Lingappa

This study shows that feline immunodeficiency virus (FIV) Gag forms assembly intermediates similar to HIV-1, involving ABCE1 and DDX6, indicating conserved viral-host interactions in lentivirus capsid assembly.

bioRxiv · Oct 22, 2017Microbiology