Author

K. Matlack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

J. C. Reed· 2 shared J. R. Lingappa· 2 shared A. F. Lingappa· 1 shared A. Kitaygorodskyy· 1 shared A. Macieik· 1 shared A. Mueller-Schiffmann· 1 shared A. R. Moreira· 1 shared B. Freeman· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

J. C. Reed

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Author profile →

2 papers

Recent·Most cited

A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex

M. Michon, A. Mueller-Schiffmann, A. F. Lingappa, S. F. Yu, L. Du, F. Deiter, S. Mallesh, J. Crabtree, U. F. Lingappa, A. Macieik, L. Mueller, P. N. Ostermann, M. Andree, O. Adams, H. Schaal, , K

The paper identifies a novel antiviral chemotype effective against multiple respiratory viruses by targeting a host multi-protein complex involved in viral lifecycle and innate immunity.

bioRxiv · Jan 17, 2021Biochemistry

Identification of an antiretroviral small molecule that appears to be a host-targeting inhibitor of HIV-1 assembly

J. C. Reed, D. Solas, A. Kitaygorodskyy, B. Freeman, D. T. B. Ressler, D. J. Phuong, J. V. Swain, K. Matlack, C. R. Hurt, V. R. Lingappa, J. R. Lingappa

This paper identifies two small molecules that inhibit HIV-1 assembly by targeting host factors involved in Gag assembly, showing efficacy against drug-resistant strains and lacking resistance mutations in Gag.

Journal of Virology · Jan 13, 2021Peer-reviewedMicrobiology