Author

J. van der Heijden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Barrueta Tenhunen· 3 shared A. Larsson· 3 shared J. Tenhunen· 3 shared P. Skorup· 2 shared A. Brown· 1 shared C. M. Miton· 1 shared D. F. Ackerley· 1 shared D. Pletzer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. Barrueta Tenhunen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis-sepsis

A. Barrueta Tenhunen, J. van der Heijden, P. Skorup, M. Maccarana, A. Larsson, A. Larsson, G. Perchiazzi, J. Tenhunen

This study tests if hyaluronan infusion improves outcomes in early peritonitis-sepsis by maintaining vascular volume, but finds no significant benefit and increased lactate levels.

bioRxiv · Apr 14, 2023 · PreprintPharmacology & Toxicology

High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in porcine abdominal sepsis

A. Barrueta Tenhunen, J. van der Heijden, W. Weigl, R. Frithiof, P. Skorup, A. Larsson, A. Larsson, J. Tenhunen

This study evaluates hyaluronan as an adjuvant to fluid resuscitation in porcine sepsis, finding no reduction in fluid volume or inflammation but a lower modified shock index.

bioRxiv · Aug 12, 2021 · PreprintPharmacology & Toxicology

Mechanistic understanding enables the rational design of salicylanilide combination therapies for Gram-negative infections

J. Copp, D. Pletzer, A. Brown, J. van der Heijden, C. M. Miton, R. J. Edgar, M. Rich, R. Little, E. Williams, R. E. W. Hancock, N. Tokuriki, D. F. Ackerley

This paper identifies mechanisms of niclosamide action and resistance in Gram-negative bacteria and demonstrates synergistic combination therapies with efflux inhibitors and membrane permeabilizers.

mBio · Oct 27, 2020Peer-reviewedMicrobiology

Does the Antisecretory Peptide AF-16 modulate fluid balance and inflammation in experimental peritonitis induced sepsis?

A. Barrueta Tenhunen, J. Tenhunen, J. van der Heijden, I. Blokhin, F. Massaro, A. Larsson, H. A. Hansson, R. Feinstein

This study tests whether AF-16 modulates sepsis symptoms in fecal peritonitis but finds no significant differences between AF-16 and saline groups.

bioRxiv · Apr 14, 2020Pathology