The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics.
P. Verdys, J. Rey Barroso, J. Vermeil, M. Bergert, T. Sanchez, A. Metais, T. Mangeat, E. Bellard, C. Bigot, J.-P. Girard, I. Maridonneau-Parini, C. Verollet, F. Lagarrigue, A. Diz-Munoz, J. Heuvingh, , R. Poincloux
This study shows that ezrin, radixin, and moesin are not required for macrophage migration or actin cortex mechanics, challenging their universal importance in these processes.
bioRxiv · Jul 27, 2023 · PreprintCell Biology