Author

J. W. Song

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 6 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

A. Avendano· 5 shared A. J. Seibel· 2 shared A. R. Bushman· 2 shared E. Akbari· 2 shared G. B. Spychalski· 2 shared K. K. Rangharajan· 2 shared M. Cortes-Medina· 2 shared M. M. Menyhert· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersBioengineering

A. Avendano

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Chondroitin sulfate, dermatan sulfate, and hyaluronic acid differentially modify the biophysical properties of collagen-based hydrogels

M. Cortes-Medina, A. R. Bushman, P. E. Beshay, J. J. Adorno, M. M. Menyhert, R. M. Hildebrand, S. S. Agarwal, A. Avendano, J. W. Song

This study examines how chondroitin sulfate, dermatan sulfate, and hyaluronic acid modify the biophysical properties of collagen hydrogels through changes in self-assembly kinetics.

bioRxiv · May 22, 2023Bioengineering

ECM-derived biophysical cues mediate interstitial flow-induced sprouting angiogenesis

C.-W. Chang, H.-C. Shih, M. Cortes-Medina, P. E. Beshay, A. Avendano, A. J. Seibel, W.-H. Liao, Y.-C. Tung, J. W. Song

This study shows hyaluronan enhances interstitial flow-induced angiogenic sprouting by altering collagen matrix stiffness and pore size.

bioRxiv · Jun 4, 2022 · PreprintBioengineering

Multiplexed Detection of Molecular Interactions with DNA Origami Engineered Cells in 3-D Collagen Matrices

M. Shahhosseini, P. Beshay, E. Akbari, A. Avendano, J. W. Song, C. Castro

The paper develops a DNA origami-based biosensor to monitor live cell interactions with biomolecules in 3-D microfluidic environments.

bioRxiv · Feb 4, 2022 · PreprintBioengineering

Endothelial Barrier Function is co-regulated at Vessel Bifurcations by Fluid Forces and Sphingosine-1-Phosphate

E. W. Akbari, G. B. Spychalski, M. M. Menyhert, K. K. Rangharajan, S. Prakash, J. W. Song

This study shows that fluid forces at vessel bifurcations and S1P signaling co-regulate endothelial barrier function, with distinct dependencies on S1P receptors.

bioRxiv · Aug 18, 2020Bioengineering

Integrated biophysical characterization of fibrillar collagen-based hydrogels

A. Avendano, J. C. Chang, M. G. Cortes-Medina, A. J. Seibel, B. R. Admasu, C. M. Boutelle, A. R. Bushman, A. A. Garg, C. M. DeShetler, S. L. Cole, J. W. Song

This paper characterizes the biophysical properties of collagen-based hydrogels using integrated methods, showing how modifications affect structure, mechanics, and transport.

bioRxiv · Dec 8, 2019Bioengineering

In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness.

C. Wormsbaecher, A. R. Hindman, A. Avendano, M. Cortes, A. Bushman, L. Onua, C. E. Kovalchin, A. R. Murphy, H. L. Helber, A. Shapiro, K. Voytovitch, X. Kuang, J. W. Song, C. J. Burd

This study shows that in utero exposure to estrogenic endocrine disruptors like BPA increases mammary gland stiffness and extracellular matrix density in adult mice, linking early-life exposure to increased breast cancer risk.

bioRxiv · Aug 30, 2019Cancer Biology

Competing Fluid Forces Control Endothelial Sprouting in a 3-D Microfluidic Vessel Bifurcation Model

E. Akbari, G. B. Spychalski, K. K. Rangharajan, S. Prakash, J. W. Song

This study investigates how fluid forces at vessel bifurcations affect endothelial sprouting in a 3D microfluidic model, finding that bifurcating flow suppresses sprouts while transvascular flow promotes them.

bioRxiv · May 3, 2019Bioengineering