Author

J. Y. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

D. Ho· 2 shared A. D. Bowen· 1 shared A. Gan· 1 shared C. Chia· 1 shared C. Li· 1 shared C. W. Chua· 1 shared C. W. Liew· 1 shared D. Luo· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

D. Ho

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4, and BA.5

Q. Wang, Y. Guo, S. Iketani, Z. Li, H. Mohri, M. Wang, J. Yu, A. D. Bowen, J. Y. Chan, J. G. Shah, N. Nguyen, Z. Chen, K. Meyers, M. T. Yin, M. E. Sobieszczyk, , D. Ho

This study analyzes antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4, and BA.5, finding BA.4/5 shows greater resistance to neutralizing antibodies than BA.2.12.1.

bioRxiv · May 26, 2022Microbiology

Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold

E. Z. K. Cheong, J. P. Quek, X. Liu, C. Li, J. Y. Chan, C. W. Liew, Y. Mu, J. Zheng, D. Luo

This paper reports the crystal structure of Rubella virus protease and demonstrates its protease and deubiquitylation activities, providing insights for antiviral drug development.

bioRxiv · Apr 15, 2022Microbiology

Liquid biopsy in gastrointestinal stromal tumors -- Simultaneous detection of primary and secondary mutations with an NGS based circulating tumor DNA assay

N. Somasundaram, R. Quek, D. Ho, M. F. B. Harunal Ras, R. R. J. Lim, A. Gan, W. L. Tan, J. Y. Chan, E. Poon, C. W. Chua, J. Ong, C. Chia, G. Tan, M. Teo, W. L. Goh, , S. B. Ng

bioRxiv · Nov 30, 2018 · PreprintMolecular Biology