Author

C. W. Chua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Califano· 1 shared A. Gan· 1 shared A. Mitrofanova· 1 shared A. Rodriguez-Calero· 1 shared A. Vasciaveo· 1 shared B. Dong· 1 shared C. Abate-Shen· 1 shared C. Chia· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. Califano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

OncoLoop: A network-based precision cancer medicine framework

A. Vasciaveo, M. Zou, J. M. Arriaga, F. Geraldes de Almeida, E. F. Douglass, M. Shibata, A. Rodriguez-Calero, S. de Brot, A. Mitrofanova, C. W. Chua, C. Karan, R. Realubit, S. Y. Pampou, J. Y. Kim, E. Corey, , C. Abate-Shen

OncoLoop predicts and validates drug sensitivity in tumors and their models by leveraging perturbational profiles of oncology drugs, showing success in prostate cancer models and patient cohorts.

bioRxiv · Feb 11, 2022Cancer Biology

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer

B. Dong, J. Miao, Y. Wang, W. Luo, Z. Ji, H. Lai, M. Zhang, X. Cheng, J. Wang, Y. Fang, H. H. Zhu, C. W. Chua, L. Fan, Y. Zhu, J. Pan, , W. Q. Gao

The paper uses single-cell RNA sequencing to show neuroendocrine prostate cancer cells originate from luminal-like cells, not basal cells, and identifies associated gene signatures.

bioRxiv · May 12, 2020Cancer Biology

Liquid biopsy in gastrointestinal stromal tumors -- Simultaneous detection of primary and secondary mutations with an NGS based circulating tumor DNA assay

N. Somasundaram, R. Quek, D. Ho, M. F. B. Harunal Ras, R. R. J. Lim, A. Gan, W. L. Tan, J. Y. Chan, E. Poon, C. W. Chua, J. Ong, C. Chia, G. Tan, M. Teo, W. L. Goh, , S. B. Ng

bioRxiv · Nov 30, 2018 · PreprintMolecular Biology