Author

J. Y. Kang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:cryo-EM· 3 Organism:bacteria (other)· 2 Assay:structural biology· 1

Frequent Co-Authors

J. Chen· 3 shared E. Llewellyn· 2 shared R. Landick· 2 shared S. A. Darst· 2 shared S. Darst· 2 shared T. V. Mishanina· 2 shared A. J. Noble· 1 shared B. T. Chait· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

J. Chen

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Author profile →

5 papers

Recent·Most cited

An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options

J. Y. Kang, T. V. Mishanina, Y. Bao, J. Chen, E. Llewellyn, J. Liu, S. A. Darst, R. Landick

This study defines an interconverting ensemble of ePEC states using cryo-EM and biochemical analysis, showing that ePECs occupy pre- or half-translocated states without always swiveling.

bioRxiv · Sep 11, 2022Biochemistry

Leadership in PhD (LeaP): a longitudinal leadership skill building program for underrepresented biomedical research trainees

M. D. Doles, J. Y. Kang, L. M. Scholl, J. D. Doles

The paper describes a 4-year leadership development program for underrepresented biomedical PhD trainees, detailing its structure, evaluation framework, and initial results.

bioRxiv · Sep 11, 2022 · PreprintScientific Communication & Education

Structural basis for transcription complex disruption by the Mfd translocase

J. Y. Kang, E. Llewellyn, J. Chen, P. D. B. Olinares, J. Brewer, B. T. Chait, E. A. Campbell, S. A. Darst

The paper uses cryo-EM to visualize Mfd interacting with stalled RNA polymerase complexes, revealing its mechanism for initiating transcription-coupled repair.

bioRxiv · Aug 12, 2020Biophysics

Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO

J. Chen, A. J. Noble, J. Y. Kang, S. Darst

This study shows that CHAPSO detergent reduces orientation bias in bacterial transcription complexes by preventing particle adsorption at the air/water interface during cryo-EM.

bioRxiv · Oct 30, 2018Biophysics

Structural basis for transcript elongation control by NusG/RfaH universal regulators

J. Y. Kang, R. A. Mooney, Y. Nedialkov, J. Saba, T. V. Mishanina, I. Artsimovitch, R. Landick, S. Darst

This study determines the structural basis of how NusG and RfaH regulate transcript elongation by suppressing backtracking and pausing in bacterial RNA polymerase complexes.

bioRxiv · May 16, 2018Biophysics