Author

R. A. Mooney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

R. Landick· 3 shared J. Saba· 2 shared T. V. Mishanina· 2 shared A. L. Gill· 1 shared D. Nayak· 1 shared E. A. Campbell· 1 shared H. Boyaci· 1 shared I. Artsimovitch· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

R. Landick

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Impact of altering gut microbiota metabolism on osteomyelitis severity in obesity-related type 2 diabetes

T. I. Bui, A. L. Gill, R. A. Mooney, S. R. Gill

This study shows that oligofructose reduces osteomyelitis severity in obese/T2D mice by altering gut microbiota and increasing polyamine production, which mediates anti-inflammatory effects.

bioRxiv · Jan 13, 2022 · PreprintMicrobiology

The elemental mechanism of transcriptional pausing

J. Saba, X. Chua, T. V. Mishanina, D. Nayak, T. A. Windgassen, R. A. Mooney, R. Landick

This study identifies the elemental pause mechanism in transcription by showing it is multipartite, causes a conformational shift, and can transition into backtracked states.

bioRxiv · Sep 19, 2018Biochemistry

Structural basis for transcript elongation control by NusG/RfaH universal regulators

J. Y. Kang, R. A. Mooney, Y. Nedialkov, J. Saba, T. V. Mishanina, I. Artsimovitch, R. Landick, S. Darst

This study determines the structural basis of how NusG and RfaH regulate transcript elongation by suppressing backtracking and pausing in bacterial RNA polymerase complexes.

bioRxiv · May 16, 2018Biophysics

Fidaxomicin jams M. tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

H. Boyaci, J. Chen, M. Lilic, M. Palka, R. A. Mooney, R. Landick, S. A. Darst, E. A. Campbell

This study determines the structure of M. tuberculosis RNA polymerase with fidaxomicin, revealing how it inhibits transcription by blocking essential motions.

bioRxiv · Jan 8, 2018Biophysics