Author

J. Zephyr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

C. A. Schiffer· 2 shared A. Ali· 1 shared A. K. Hedger· 1 shared A. N. Matthew· 1 shared D. N. Rao· 1 shared E. T. Chan· 1 shared J. Timm· 1 shared K. KosovrastiiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

C. A. Schiffer

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2 papers

Recent·Most cited

FruitFire: a luciferase based on a fruit fly metabolic enzyme

S. T. Adams, J. Zephyr, M. F. Bohn, C. A. Schiffer, S. C. Miller

The paper describes the creation of an artificial luciferase, FruitFire, by modifying a fruit fly enzyme to enable in vivo bioluminescence imaging.

bioRxiv · Jun 30, 2023 · PreprintBiochemistry

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

J. Zephyr, D. N. Rao, S. V. Vo, M. Henes, K. Kosovrasti, A. N. Matthew, A. K. Hedger, J. Timm, E. T. Chan, A. Ali, N. K. Yilmaz, C. A. Schiffer

The paper investigates how fluorination of HCV protease inhibitors improves resistance to the D168A variant by enabling alternate binding conformations through co-crystal structure analysis.

Journal of Molecular Biology · May 1, 2022Peer-reviewedBiochemistry