Cancer BiologybioRxiv
SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia
L. H. Geraldo, Y. Xu, L. Jacob…·T. Mathivet
This study shows that SLIT2-ROBO signaling in tumor-associated microglia/macrophages promotes glioblastoma immunosuppression and vascular dysmorphia, and its inhibition reduces tumor growth and enhances therapy.