Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohns Disease
Ingrid Jurickova, Benjamin W. Dreskin, Elizabeth B. Angerman, Erin L. Bonkowski, Jack Nguyen, Richard Villarreal, Kentaro Tominaga, Kentaro Iwasawa, Tzipi Braun, Takanori Takebe, Michael A. Helmrath, Yael Haberman, James M. Wells, Lee A. Denson
The paper tests eicosatetraynoic acid (ETYA) in a human intestinal organoid model to suppress pro-fibrotic pathways in macrophages associated with Crohn's Disease.
Journal of Crohn s and Colitis · Aug 30, 2024Peer-reviewedMolecular Biology