Macrophages Mediate Antiviral Immunity and Repair of Type 2 Alveolar Epithelial Cells in a Human Stem Cell Model
Declan L. Turner, Hannah Baric, Katelyn Patatsos, Sahel Amoozadeh, Michael See, Kathleen A. Strumila, Jack T. Murphy, Liam Gubbels, Elizabeth Ng, Andrew G. Elefanty, Melanie R. Neeland, Shivanthan Shanthikumar, Sarah L. Londrigan, Mirana Ramialison, Fernando Jaime Rossello, , Rhiannon B. Werder
This study develops an iPSC-derived air-liquid interface platform to study AT2-macrophage interactions in homeostasis, infection, and repair, revealing their roles in antiviral immunity and epithelial repair.
bioRxiv · Apr 15, 2025 · PreprintCell Biology