Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females
Puja Biswas, Jacob Bako, J. Beatrice Liston, Huaxu Yu, Lianna W. Wat, Colin J. Miller, Michael D. Gordon, Tao Huan, Molly Stanley, Elizabeth J. Rideout
This study identifies the insulin/insulin-like growth factor signaling pathway as a key determinant of higher fat storage in Drosophila females through increased dietary sugar intake and Dilp3 expression.
Cell Reports · Jul 1, 2025Peer-reviewedPhysiology