Huaxu Yu

This study shows that SARS-CoV-2 deISGylation by PLpro suppresses innate immunity and promotes viral replication by modulating cellular metabolism.

This study identifies the insulin/insulin-like growth factor signaling pathway as a key determinant of higher fat storage in Drosophila females through increased dietary sugar intake and Dilp3 expression.

This study investigates how early-life gut inflammation affects microbiome, endocrine, and behavioral outcomes, revealing sex-specific impacts on microbiota composition, hormone levels, and behavior.

The paper introduces ms1-id, a tool for structural annotation of MS1 data in LC-MS and MS imaging, enabling level 2/3 annotation and uncovering previously overlooked metabolites.

This paper introduces BAGO, a Bayesian optimization method for optimizing LC gradients in untargeted LC-MS, improving compound annotation and spectral purity.

This study identifies triglyceride as a key neutral lipid regulating spermatogenesis in Drosophila by showing that loss of the triglyceride lipase brummer leads to sperm developmental defects.

MAFFIN improves metabolomics sample normalization by using maximal density fold change with high-quality features and signal correction, enhancing data separation and metabolic feature detection.