Author

Jacob H Schroader

State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex M. ValmiD· 1 shared Bradley R. Smith· 1 shared Cara Theresia PageriD· 1 shared Emmanuel E. AdadeiD· 1 shared Gabriele FuchsiD· 1 shared Hannah K. ShorrockiD· 1 shared J. Andrew BerglundiD· 1 shared Kaalak ReddyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alex M. ValmORCID

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1 paper

Recent·Most cited

Inosine misincorporation into mRNA triggers the integrated stress response and activates an innate immune gene expression signature

Jacob H Schroader, Naa N. Adade, Emmanuel E. Adade, Mark A. Bratslavsky, Hannah K. Shorrock, Bradley R. Smith, Ting Zhou, Steven Lotz, Taylor B. Bertucci, Sally Temple, Alex M. Valm, Cara Theresia Pager, J. Andrew Berglund, Mark T. Handley, Gabriele Fuchs, Kaalak Reddy

This study shows that inosine misincorporation into mRNA activates the integrated stress response and an innate immune gene expression signature, linking ITPase deficiency to cellular stress.

bioRxiv · Jan 17, 2026 · PreprintMolecular Biology