Author

Jacqueline Ming Shen

Ragon Institute of MGH, MIT and Harvard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alessia LiguoriiD· 1 shared Alexandra Vernich· 1 shared Ali A. AlbowaideyiD· 1 shared Anthony Alicea· 1 shared Arianna EspositoiD· 1 shared Bingxian CheniD· 1 shared Brendon Kelley· 1 shared Christopher A. CottrelliD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperImmunology

Alessia LiguoriORCID

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1 paper

Recent·Most cited

Antibody feedback establishes an affinity brake in the germinal center

Yu Yan, Xuesong Wang, Zhenfei Xie, Daniel L. V. Bader, Ryan H. Lim, Krystal M. Ma, Christopher A. Cottrell, Jon M. Steichen, Liling Xu, Paula Maldonado Villavicencio, Madhav Akauliya, Ja‐Hyun Koo, Jacqueline Ming Shen, Alexandra Vernich, Oleksandr Kalyuzhniy, , Facundo D. Batista

The paper investigates how B cell affinity affects germinal center (GC) responses by showing high-affinity B cells have shorter GC residence times and lower-affinity B cells are maintained, suggesting an antibody feedback mechanism that modulates affinity and epitope spreading.

bioRxiv · Nov 13, 2025 · PreprintImmunology