Author

Jacques A. Bertrand

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Ross EthieriD· 2 shared Cydney A. WongiD· 2 shared Darryl R. OverbyiD· 2 shared Haiyan LiiD· 2 shared Kristin M. Perkumas· 2 shared Seyed Mohammad SiadatiD· 2 shared William Daniel StameriD· 2 shared A. Thomas ReadiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

C. Ross EthierORCID

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Author profile →

2 papers

Recent·Most cited

Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores

Seyed Mohammad Siadat, Haiyan Li, Brigid A. Millette, Babak N. Safa, Cydney A. Wong, Mohammad Reza Bahrani Fard, Sietse T. Braakman, Ian Tay, Jacques A. Bertrand, A. Thomas Read, Lisa A. Schildmeyer, Kristin M. Perkumas, William Daniel Stamer, Darryl R. Overby, C. Ross Ethier

This study shows that endothelial cell stiffness and type influence biomechanically-induced transcellular pore formation in Schlemms canal cells.

Cell Reports · Dec 17, 2025Peer-reviewedBioengineering

TRPV4 modulates substrate stiffness mechanosensing and transcellular pore formation in human Schlemm's canal cells

Haiyan Li, Cydney A. Wong, Seyed Mohammad Siadat, Kristin M. Perkumas, Jacques A. Bertrand, Darryl R. Overby, Todd Sulchek, William Daniel Stamer, C. Ross Ethier

This study shows TRPV4 modulates substrate stiffness sensing and transcellular pore formation in Schlemm's canal cells, with implications for glaucoma treatment.

bioRxiv · May 25, 2025 · PreprintCell Biology