An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics
Colette Lafontaine Picard, Lucia Ichino, Tyler J. Buckley, Brandon A. Boone, Jaewon Yun, Kevin Daniel Abuhanna, Yi Zhang, Noah J. Behrendt, Su May Lei Soe, Chongyuan Luo, Steven E. Jacobsen
The paper reveals an antagonistic epigenetic mechanism in Arabidopsis pollen where MBD5/6 repress methylated loci while MBD7 promotes demethylation and transcriptional activation.
Nature Communications · Nov 27, 2025Peer-reviewedMolecular Biology