Developmental BiologybioRxivPreprint
Whole embryo barcoding reveals convergent origins of mesodermal cells during mammalian gastrulation
Marine A Secchi, Peter J Martin, Jake Cornwall-Scoones…·Sarah Bowling
The paper uses CRISPR-based lineage recording and single-cell RNA sequencing to show that mesodermal cell diversity in mouse embryos arises from spatially distinct, fate-biased progenitor pools rather than simple branching lineages.