Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice
Alexandra Fischer, Hanah B. Robertson, Deqiang Kong, Merlin M. Grimm, Jakob Grether, Johanna Groth, Carsten Baltes, Manfred Fliegauf, Franziska Lautenschläger, Bodo Grimbacher, Haifeng Ye, Volkhard Helms, Wilfried Weber
This study tunes the material properties of transcription factor condensates to show their impact on gene expression levels in mammalian cells and mice.
Small · Apr 4, 2024Peer-reviewedSynthetic Biology