Bidirectional Crosstalk Between Sleep and Pulmonary Arterial Hypertension
Seun Imani, Aymen Halouani, Jacob Dahlka, Nathan Burgess, Samar Antar, You‐Yang Zhao, Stephen Y. Chan, James D West, Matthew Weston, Yassine Sassi
This study shows poor sleep worsens pulmonary arterial hypertension (PAH) by inducing inflammation and PASMC proliferation, forming a self-amplifying cycle that can be mitigated by improving sleep and reducing inflammation.
bioRxiv · Jul 23, 2025 · PreprintPathology