You‐Yang Zhao

CD133+ progenitor cells promote pulmonary hypertension through CXCR4 signaling

This study identifies CD133+ progenitor cells as contributors to pulmonary hypertension and shows that CXCR4 signaling drives their pathogenic role in vascular remodeling.

Bidirectional Crosstalk Between Sleep and Pulmonary Arterial Hypertension

This study shows poor sleep worsens pulmonary arterial hypertension (PAH) by inducing inflammation and PASMC proliferation, forming a self-amplifying cycle that can be mitigated by improving sleep and reducing inflammation.

Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension

The paper identifies FABP4/5 as key regulators of endothelial glycolysis and arterial programming in pulmonary hypertension using single-cell and spatial transcriptomics.

General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension through HIF-2α/Notch4 Pathway

Decitabine Reactivation of FoxM1-Dependent Endothelial Regeneration and Vascular Repair for Potential Treatment of Elderly ARDS and COVID-19 Patients

This study shows that Decitabine can reactivate FoxM1-dependent vascular repair in aged mice, improving survival after sepsis and suggesting potential treatment for elderly ARDS and COVID-19 patients.