Author

Seun Imani

Virginia Tech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aymen HalouaniiD· 3 shared Yassine SassiiD· 3 shared Jacob DahlkaiD· 2 shared Samar Antar· 2 shared Aanandi Parashar· 1 shared Ahmed RaslaniD· 1 shared Diego FraidenraichiD· 1 shared Eric Mensah· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersPathology

Aymen HalouaniORCID

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3 papers

Recent·Most cited

Paracrine Action of Bone Morphogenetic Protein 3 in Pulmonary Arterial Hypertension

Aymen Halouani, Eric Mensiah, Mariem Ben Rhouma, Zaujia Athumani, Michael G. Katz, Seun Imani, Samar Antar, Katherine Jankowski, Maryam Mansoori, Vicki Rosen, Kiyotake Ishikawa, Lahouaria Hadri, Yassine Sassi

This study shows that BMP3 overexpression reduces pulmonary vascular remodeling and cardiac dysfunction in PAH by balancing TGF-β and BMP pathways through paracrine signaling.

European Respiratory Journal · Jul 30, 2026Peer-reviewedPathology

A Simultaneous Inhibition of ID1 and ID3 Protects Against Pulmonary Fibrosis

Samar A. Antar, Eric Mensah, Jacob Dahlka, Muhammad Mirza Abdul Aziz, Aymen Halouani, Seun Imani, Aanandi Parashar, Ahmed Raslan, Robert Benezra, Diego Fraidenraich, Giovanni Ligresti, Yassine Sassi

This study shows that inhibiting both ID1 and ID3 reduces pulmonary fibrosis in mice and human cells by blocking fibroblast proliferation and differentiation.

bioRxiv · Jul 24, 2025 · PreprintPathology

Bidirectional Crosstalk Between Sleep and Pulmonary Arterial Hypertension

Seun Imani, Aymen Halouani, Jacob Dahlka, Nathan Burgess, Samar Antar, You‐Yang Zhao, Stephen Y. Chan, James D West, Matthew Weston, Yassine Sassi

This study shows poor sleep worsens pulmonary arterial hypertension (PAH) by inducing inflammation and PASMC proliferation, forming a self-amplifying cycle that can be mitigated by improving sleep and reducing inflammation.

bioRxiv · Jul 23, 2025 · PreprintPathology