Author

James E. Dowling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adrian S. RayiD· 1 shared Alice Bourgeois· 1 shared Andréanne Pelletier· 1 shared Blaise Lippa· 1 shared Bryan Goodwin· 1 shared Charlie Théberge· 1 shared Charlotte RomanetiD· 1 shared François PotusiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Adrian S. RayORCID

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1 paper

Recent·Most cited

Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights from Comprehensive Multicenter Preclinical Studies

Sarah-Eve S Lemay, Mónica S. Montesinos, Yann Grobs, Tetsuro Yokokawa, Tsukasa Shimauchi, Manon Mougin, Charlotte Romanet, Mélanie Sauvaget, Sandra Breuils‐Bonnet, Alice Bourgeois, Charlie Théberge, Andréanne Pelletier, Reem El Kabbout, Sandra Martineau, Keiko Yamamoto, , Sébastien Bonnet

The study identifies integrin α5β1 as a key driver of pulmonary vascular remodeling in PAH and shows its inhibition improves hemodynamics and RV function in preclinical models.

Circulation · Jan 20, 2025Peer-reviewedPathology