Author

James Hall

Max Delbrück CenterPrimary ORCID profile (0009-0001-3827-853X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

James HalliD1 paper · University of Sheffield

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Angela Tzu-Lun HuangiD· 1 shared Ava P. AminiiD· 1 shared Charles SwantoniD· 1 shared Clément VerkestiD· 1 shared Dimana Kaludova· 1 shared Eric ZimmermanniD· 1 shared Fabian Joachim TheisiD· 1 shared Filipe Correia MartinsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

Angela Tzu-Lun HuangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Single-cell mapping of the fallopian tube reveals a genomically unstable secretory cell state enriched in carriers of germline BRCA1/2 mutations

Yaniv Eyal-Lubling, Maria Vias, Katarzyna Kania, Dimana Kaludova, James Hall, Robin Crawford, Rutendo Nyagumbo, Sophia Ward, Svetlana Khoronenkova, Samuel A. J. R. Aparicio, Charles Swanton, Mercedes Jimenez Linan, James D. Brenton, Filipe Correia Martins

The paper identifies genomically unstable secretory cells in fallopian tubes of BRCA1/2 carriers using single-cell transcriptomics, linking them to replication stress and early cancer transformation.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology

Beyond alignment: synergistic integration is required for multimodal cell foundation models

Till Richter, Eric Zimmermann, James Hall, Fabian Joachim Theis, Srivatsan Raghavan, Peter S. Winter, Ava P. Amini, Lorin A. Crawford

This paper introduces a metric to evaluate synergistic integration in multimodal cell models and shows when it benefits tasks over unimodal approaches.

bioRxiv · Mar 2, 2026 · PreprintBioinformatics

Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells

Clément Verkest, Lucas Roettger, Nadja Zeitzschel, James Hall, Oscar Sánchez-Carranza, Angela Tzu-Lun Huang, Gary R. Lewin, Stefan G. Lechner

This study uses MINFLUX nanoscopy to show PIEZO1 channels create membrane invaginations and exhibit conformational changes linked to function and cytoskeletal architecture in intact cells.

Science Advances · Oct 22, 2025Peer-reviewedCell Biology