In vitro host transcriptomics during Cryptococcus neoformans, Cryptococcus gattii, and Candida albicans infection of South African volunteers
Ronan Doyle, Shichina Kannambath, Alan Michael Pittman, Rene T. Goliath, Vinod Kumar, Graeme Meintjes, James Milburn, Mihai Gheorghe Netea, Thomas Stephen Harrison, Joseph N Jarvis, Tihana A. Bicanic
The paper compares the transcriptional responses of immune cells to three fungal pathogens in vitro, finding distinct expression patterns and a weaker response to cryptococcal stimuli.
bioRxiv · Apr 5, 2024 · PreprintGenomics