Thomas Stephen Harrison

This paper develops a subunit vaccine, Burulivac, that fully protects mice against Buruli ulcer in a footpad model by inducing protective immune responses.

The paper compares the transcriptional responses of immune cells to three fungal pathogens in vitro, finding distinct expression patterns and a weaker response to cryptococcal stimuli.

This study links genetic variation in Cryptococcus neoformans to clinical outcomes and virulence in animal models using GWAS and genomic data from 284 isolates.

This study analyzes the population genomics of Cryptococcus neoformans var. grubii, revealing hybridization, biogeographic relationships, and genetic structure across global isolates.

The paper uses whole-genome sequencing to determine whether recurrent cryptococcal meningitis in HIV patients results from relapse or reinfection, finding clonal relationships in most cases and novel hypermutator mechanisms in others.