Author

Jana Bláhová

Czech Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alena RandákováiD· 1 shared Allan I. BasbaumiD· 1 shared Anni AllikaltiD· 1 shared Annika Ullrich· 1 shared Asuka InoueiD· 1 shared Barbora SvobodováiD· 1 shared Bettina BöttcheriD· 1 shared Brian K. ShoichetiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alena RandákováORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyBiomedicine & PharmacotherapyPeer-reviewedOct 22, 2025

Balancing Rigidity and Flexibility: Optimised 4-(Hexyloxy)benzoate Antagonists with Enhanced Affinity and Tuneable Duration at Muscarinic Receptors

Eva Dolejší, Eva Mezeiová, Jana Bláhová…·Ján Jakubík

This study synthesizes and evaluates 4-(hexyloxy)benzoate derivatives to optimize muscarinic receptor antagonists, finding that rigid groups increase affinity but reduce duration, while flexible analogues balance potency and residence time.

DOI 10.1016/j.biopha.2025.118653

mechanistic / dynamical modeldrug response / drug discovery

𝕏 PostBluesky

Pharmacology & ToxicologyScience AdvancesPeer-reviewedJun 18, 2025

Discovery of a functionally selective serotonin 5-HT1A receptor agonist for the treatment of pain

Annika Ullrich, Johannes Schneider, João M. Bráz…·Peter Gmeiner

The paper identifies ST171, a selective 5-HT1A receptor agonist effective in pain models without sedation, and elucidates its mechanism through structural and computational analysis.

18 citations

mouseproteomics

𝕏 PostBluesky