Clec7a-mediated regulation of Killer-like Lectin Receptor expression controls T cell immunity
Ivy M. Dambuza, Fabián Salazar, Emily A Sey, Stavroula Lila Kastora, Cecilia Rodrigues, Annie Phillips-Brookes, Jamie Harvey, Rebecca A. Drummond, Jane Rush, Raif Yuecel, Shinobu Saijo, Janet A. Willment, Daniel H. Kaplan, Salomé LeibundGut‐Landmann, Gordon D. Brown
This study identifies a novel Clec7a-KLR axis that regulates DC function and CD4 T cell responses, linking innate and adaptive immunity in host defense and inflammation.
bioRxiv · Dec 9, 2025 · PreprintImmunology