Daniel H. Kaplan

immgenT creates a comprehensive T-cell molecular atlas across mouse organs and disease states, identifying 8 lineages and 107 clusters using deep generative models and integrating external datasets.

This study shows Dectin-2 is essential for controlling Candida albicans in the intestine despite normal T cell activation, by regulating neutrophil function and IL-17A/GM-CSF responses.

This study shows that antigen encounter in the epidermis enhances TRM persistence and proliferation through TGF{beta} signaling and TGF{beta}RIII expression.

This study identifies a novel Clec7a-KLR axis that regulates DC function and CD4 T cell responses, linking innate and adaptive immunity in host defense and inflammation.