Author

Janet A. Willment

University of ExeterORCID 0000-0002-7040-0857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Cecilia RodriguesiD· 2 shared Emily A SeyiD· 2 shared Fabián SalazariD· 2 shared Gordon D. BrowniD· 2 shared Ivy M. DambuzaiD· 2 shared Jamie Harvey· 2 shared Salomé LeibundGut‐LandmanniD· 2 shared Andrew MatthewsiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Cecilia RodriguesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clec7a-mediated regulation of Killer-like Lectin Receptor expression controls T cell immunity

Ivy M. Dambuza, Fabián Salazar, Emily A Sey, Stavroula Lila Kastora, Cecilia Rodrigues, Annie Phillips-Brookes, Jamie Harvey, Rebecca A. Drummond, Jane Rush, Raif Yuecel, Shinobu Saijo, Janet A. Willment, Daniel H. Kaplan, Salomé LeibundGut‐Landmann, Gordon D. Brown

This study identifies a novel Clec7a-KLR axis that regulates DC function and CD4 T cell responses, linking innate and adaptive immunity in host defense and inflammation.

bioRxiv · Dec 9, 2025 · PreprintImmunology

KLRE1 shapes antifungal immunity by tuning dendritic cell and T cell activation through distinct heterodimeric partners

Fabián Salazar, Ivy M. Dambuza, Emily A Sey, Cecilia Rodrigues, Mariano Malamud, Jamie Harvey, Janet A. Willment, Salomé LeibundGut‐Landmann, Gordon D. Brown

This paper identifies KLRE1 as a regulator of dendritic cell and T cell activation through heterodimeric interactions with KLRI1 and KLRI2, influencing immune outcomes during fungal infection.

bioRxiv · Dec 5, 2025 · PreprintImmunology

Antagonism between bacteriophages and macrophages decreases efficacy of a phage cocktail and increases bacteriophage resistance

Meaghan Castledine, Zuzanna Szczutkowska, Andrew Matthews, Sarah K. Walsh, Rai Lewis, Suzanne Kay, Janet A. Willment, Gordon D. Brown, Angus G. J. Buckling

This study shows macrophages reduce bacteriophage efficacy and increase bacterial resistance in Pseudomonas aeruginosa during phage therapy.

bioRxiv · May 16, 2025 · PreprintEvolutionary Biology