Gordon D. Brown

This study shows Dectin-2 is essential for controlling Candida albicans in the intestine despite normal T cell activation, by regulating neutrophil function and IL-17A/GM-CSF responses.

This study identifies a novel Clec7a-KLR axis that regulates DC function and CD4 T cell responses, linking innate and adaptive immunity in host defense and inflammation.

This paper identifies KLRE1 as a regulator of dendritic cell and T cell activation through heterodimeric interactions with KLRI1 and KLRI2, influencing immune outcomes during fungal infection.

This study shows that Mgl2+ cDC2s trigger fungal allergic inflammation through a glycolytic shift driven by glucose availability after spore uptake.

This paper develops a CRISPR/Cas9-based transformation protocol for targeted gene manipulation in Sporothrix species, enhancing gene deletion efficiency by deleting the KU80 homologue.