Ivy M. Dambuza

This study uses a repeated low-dose inhalation model in genetically diverse mice to show that pulmonary immune responses influence granuloma formation and neuroinvasive disease in cryptococcal infection.

This study shows that Cryptococcus gattii adapts to mycobacterial exposure by altering its structure and increasing pulmonary persistence in a co-infection model.

This study shows that Cryptococcus neoformans changes its morphology and capsule when exposed to mycobacteria, potentially worsening co-infection outcomes.

This study shows Dectin-2 is essential for controlling Candida albicans in the intestine despite normal T cell activation, by regulating neutrophil function and IL-17A/GM-CSF responses.

This study identifies a novel Clec7a-KLR axis that regulates DC function and CD4 T cell responses, linking innate and adaptive immunity in host defense and inflammation.

This paper identifies KLRE1 as a regulator of dendritic cell and T cell activation through heterodimeric interactions with KLRI1 and KLRI2, influencing immune outcomes during fungal infection.