More than 16,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells
Laura Gómez-Valero, Christophe Rusniok, Danielle Carson, Sonia Mondino, Ana Elena Pérez‐Cobas, Monica Rolando, Shivani Pasricha, Sandra Reuter, Jasmin Demirtas, Johannes Crumbach, Stéphane Descorps‐Declère, Elizabeth Louise Hartland, Sophie Jarraud, Gordon Dougan, Gunnar N. Schroeder, , Carmen Buchrieser
The paper identifies over 16,000 secreted proteins in Legionella species, revealing their ability to acquire eukaryotic-like genes for intracellular replication in human cells.
Proceedings of the National Academy of Sciences · Jan 18, 2019Peer-reviewedGenomics