Monica Rolando

This study identifies L. pneumophila's LpDot1 protein as a bacterial effector that modifies SFPQ, disrupting paraspeckle organization and host splicing, leading to alternative splice variants of infection-related genes.

This paper shows that the Legionella pneumophila effector LegK1 suppresses RNA silencing by interacting with Argonaute proteins and activating NF-κB signaling, enhancing bacterial virulence.

The paper identifies over 16,000 secreted proteins in Legionella species, revealing their ability to acquire eukaryotic-like genes for intracellular replication in human cells.