Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomas
Dawei Zhou, Guillaume N. Fiches, Zhenyu Wu, Suha Eleya, Youngmin Park, Jinshan He, K.A.S.N. Shanaka, Thurbu Tshering Lepcha, Yan Liu, Jason Oliva, Kathryn Anne Lurain, Jae Ung Jung, Jun Qi, Weiqiang Zhao, Jian Zhu, Netty G. Santoso
This study shows that inhibiting KDM5A/B enhances antitumor innate immune responses and induces KSHV lytic reactivation in KSHV-positive B-cell lymphomas.
npj Viruses · Aug 22, 2026Peer-reviewedMicrobiology