Jae Ung Jung

This study identifies OASL as an inhibitor of ADAR1 p150, showing it limits RNA binding and A-to-I editing while modulating antiviral immunity.

This study identifies a cholesterol-dependent mechanism by which the KSHV GPCR ORF74 regulates its constitutive activity through structural and functional analysis.

This study shows that inhibiting KDM5A/B enhances antitumor innate immune responses and induces KSHV lytic reactivation in KSHV-positive B-cell lymphomas.

The paper develops an in silico-in vitro workflow to generate high-affinity antibodies targeting the KRAS(G12D)-MHC I complex, achieving nanomolar affinity and specific T cell activation.

The paper examines sex differences in COVID-19 outcomes and immune responses using single-cell RNA-sequencing and clinical data, finding higher risk for males and potential mechanisms for sex-specific treatments.