A Genetic Model Therapy Proposes a Critical Role for Liver Dysfunction in Mitochondrial Biology and Disease
Ankit Sabharwal, Mark D. Wishman, Roberto Lopez Cervera, MaKayla R. Serres, Jennifer Lynn Anderson, Shannon R. Holmberg, Bibekananda Kar, Anthony J. Treichel, Noriko Ichino, Weibin Liu, Jingchun Yang, Yonghe Ding, Yun Deng, Jean M. Lacey, William J. Laxen, , Stephen Carl Ekker
This paper presents a zebrafish model of Leigh Syndrome, demonstrating liver dysfunction's critical role in mitochondrial disease through genetic rescue.
eLife · Nov 21, 2022Peer-reviewedGenetics