Weibin Liu

A Genetic Model Therapy Proposes a Critical Role for Liver Dysfunction in Mitochondrial Biology and Disease

This paper presents a zebrafish model of Leigh Syndrome, demonstrating liver dysfunction's critical role in mitochondrial disease through genetic rescue.

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

This study uses Mendelian randomization to identify causal relationships between gut microbiome composition and blood metabolites in a Chinese cohort.

Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome

This study identifies genetic loci associated with the oral microbiome using metagenome-genome-wide association studies in over 1,915 individuals.

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

This paper performs M-GWAS on a Chinese cohort to identify genetic contributions to the gut microbiome and its associations with complex diseases.

The Vertebrate Codex Gene Breaking Protein Trap Library For Genomic Discovery and Disease Modeling Applications

The paper describes a zebrafish gene break transposon library for genomic discovery and disease modeling, identifying novel gene expression patterns and generating models for human disease loci.

Engineering targeted deletions in the mitochondrial genome

This paper introduces a method to engineer precise deletions in the mitochondrial genome using TALE proteins in zebrafish and human cells.