Author

Jean Quentin

New York Genome Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Dan Avi LandauiD· 2 shared Srinivas RajagopalaniD· 2 shared Adam J. WidmaniD· 1 shared Aditya S. DeshpandeiD· 1 shared Alexandre Pellan ChengiD· 1 shared Amanda FrydendahliD· 1 shared Andrew J. J. MungalliD· 1 shared Anushri AroraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Dan Avi LandauORCID

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2 papers

Recent·Most cited

Single-Cell Sequencing Reveals Extensive Genetic Diversity Underlying Pediatric ALL Treatment Complexity

Yakun Pang, Tamara Prieto, Veronica Gonzalez-Pena, Athena Aragon, Yuntao Xia, Sheng Kao, Srinivas Rajagopalan, John Zinno, Jean Quentin, Julien Laval, Dennis J. Yuan, Nathaniel D. Omans, Catherine Potenski, David Klein, Matthew J. MacKay, , Charles Gawad

The paper uses single-cell sequencing to uncover hidden genetic diversity in pediatric ALL that is not detected by bulk sequencing, identifying treatment-resistant clones and their associated mutations.

bioRxiv · Mar 19, 2025 · PreprintCancer Biology

Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring

Adam J. Widman, Minita J. Shah, Amanda Frydendahl, Daniel Halmos, Cole C. Khamnei, Nadia Øgaard, Srinivas Rajagopalan, Anushri Arora, Aditya S. Deshpande, William F. Hooper, Jean Quentin, Jake Bass, Mingxuan Zhang, Theophile Langanay, Laura Andersen, , Dan Avi Landau

This paper introduces MRD-EDGE, a machine learning platform for ultrasensitive ctDNA detection in plasma WGS, showing improved sensitivity and broader applicability for MRD monitoring.

Nature Medicine · Jun 1, 2024Peer-reviewedGenomics