Cell BiologyMolecular Biology of the CellPeer-reviewed
Steady-state epithelial apical flatness is characterized by MLCK morphodynamics and asynchronous Ca2+ oscillations, but not underlying ECM geometry
Hao Wu, Emerson Herrmann, Jeanette D. Hyer…·Takashi Mikawa
This study shows that apical flatness in epithelial tissues is maintained by MLCK-driven myosin II dynamics and asynchronous Ca2+ oscillations, independent of basement membrane geometry.