The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing
Z. Hong Zhou, Shiheng Liu, Tiantian Su, Jeffrey Huang, Chia-Ho Lin, Douglas L. Black, Andrey Damianov
This study identifies RBM5's role in regulating splicing by activating DHX15 and blocking spliceosome progression, with implications for cancer-related splicing dysregulation.
bioRxiv · Mar 27, 2026 · PreprintMolecular Biology