Shiheng Liu

The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing

This study identifies RBM5's role in regulating splicing by activating DHX15 and blocking spliceosome progression, with implications for cancer-related splicing dysregulation.

Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

This study uses cryoET and deep learning to reveal structural differences in the tegument and envelope of EBV and KSHV virions compared to other herpesviruses.

Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney

The paper reports cryoEM structures of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney, revealing structural differences and insights into their organization.