Author

Jenet K. Matlack

University of South Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Jameela LokhandwalaiD· 2 shared Jennifer M. BinningiD· 2 shared Robert E MineriD· 2 shared Alexa D. GannoniD· 1 shared Angelo A. NicolaciiD· 1 shared Kim C. TraniD· 1 shared Michael N. TengiD· 1 shared Nina ObertoppiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Jameela LokhandwalaORCID

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3 papers

Recent·Most cited

Ancestral protein reconstruction reveals the mechanism of substrate specificity in FN3K-mediated deglycation.

Jenet K. Matlack, Robert E Miner, Jameela Lokhandwala, Jennifer M. Binning

This study uses ancestral protein reconstruction to uncover the molecular mechanism of substrate specificity in FN3K and KT3K enzymes, revealing an allosteric network that modulates substrate recognition.

Communications Biology · Apr 3, 2026Peer-reviewedBiochemistry

Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer

Tracess B. Smalley, Angelo A. Nicolaci, Kim C. Tran, Jameela Lokhandwala, Nina Obertopp, Jenet K. Matlack, Robert E Miner, Michael N. Teng, Shari Pilon‐Thomas, Jennifer M. Binning

This study develops a PROTAC that degrades HPV E6 protein, reducing tumor burden in a mouse model and showing immune dependence.

Molecular Therapy · Aug 26, 2025Peer-reviewedMolecular Biology

Exploring aggregation genes in a P. aeruginosa chronic infection model

Alexa D. Gannon, Jenet K. Matlack, Sophie E. Darch

This study identifies genes essential for Pseudomonas aeruginosa aggregate formation in CF sputum using RNA-seq and microscopy, revealing distinct spatial phenotypes and cooperative interactions.

Journal of Bacteriology · Dec 11, 2024Peer-reviewedMicrobiology