Molecular BiologyMolecular TherapyPeer-reviewed
Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer
Tracess B. Smalley, Angelo A. Nicolaci, Kim C. Tran…·Jennifer M. Binning
This study develops a PROTAC that degrades HPV E6 protein, reducing tumor burden in a mouse model and showing immune dependence.
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