Angelo A. Nicolaci

This study shows that high-risk HPV E7 proteins require inactivating both RB1 and PTPN14 to extend keratinocyte lifespan, while low-risk E7 needs PTPN14 inactivation alone.

This study identifies circPMS1 as a pro-metastatic circRNA in melanoma that promotes cytoskeletal remodeling and metastasis by scaffolding LIM proteins.

This study identifies QPRT as a non-canonical apoptosis regulator in NSCLC that suppresses caspase-3 activation, independent of its role in NAD biosynthesis, suggesting it as a therapeutic target.

This study develops a PROTAC that degrades HPV E6 protein, reducing tumor burden in a mouse model and showing immune dependence.