BiochemistrybioRxivPreprint
Balancing spatial resolution and proteome depth in LC-MS based spatialproteomics
Mandy Meijer, Jeongwoo Hong, Tobias T. Pohl…·Ilaria Piazza
This study evaluates the trade-off between spatial resolution and proteome depth in spatial proteomics using SLACS, showing that few-cell sampling maintains proteomic information while increasing spatial specificity.
DOI 10.64898/2026.08.27.747491